Cargando…

Making Sense of the Epigenome Using Data Integration Approaches

Epigenetic research involves examining the mitotically heritable processes that regulate gene expression, independent of changes in the DNA sequence. Recent technical advances such as whole-genome bisulfite sequencing and affordable epigenomic array-based technologies, allow researchers to measure e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cazaly, Emma, Saad, Joseph, Wang, Wenyu, Heckman, Caroline, Ollikainen, Miina, Tang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390500/ https://www.ncbi.nlm.nih.gov/pubmed/30837884 http://dx.doi.org/10.3389/fphar.2019.00126

Ejemplares similares

Modeling dependency structures in 450k DNA methylation data
por: Nustad, Haakon E, et al.
Publicado: (2021)

An integrative machine learning approach to discovering multi-level molecular mechanisms of obesity using data from monozygotic twin pairs
por: Kibble, Milla, et al.
Publicado: (2020)

The Epigenomics of Embryonic Pathway Signaling in Colorectal Cancer
por: Balch, Curt, et al.
Publicado: (2017)

Mendelian randomization in (epi)genetic epidemiology: an effective tool to be handled with care
por: Latvala, Antti, et al.
Publicado: (2016)

Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci
por: Gupta, Richa, et al.
Publicado: (2019)

Toward an Integrative Approach for Making Sense Distinctions
por: McCrae, John P., et al.
Publicado: (2022)

An Integrated Pharmacological Counselling Approach to Guide Decision-Making in the Treatment with CDK4/6 Inhibitors for Metastatic Breast Cancer
por: Roncato, Rossana, et al.
Publicado: (2022)

The potential of DNA methylation as a biomarker for obesity and smoking
por: Heikkinen, Aino, et al.
Publicado: (2022)

IpiRId: Integrative approach for piRNA prediction using genomic and epigenomic data
por: Boucheham, Anouar, et al.
Publicado: (2017)

Big Data and Real-World Data based Cost-Effectiveness Studies and Decision-making Models: A Systematic Review and Analysis
por: Lu, Z. Kevin, et al.
Publicado: (2021)

Corrigendum: Big Data and Real-World Data Based Cost-Effectiveness Studies and Decision-Making Models: A Systematic Review and Analysis
por: Lu, Z. Kevin, et al.
Publicado: (2022)

Making sense of data : a self-instruction manual on the interpretation of epidemiological data
por: Abramson, J. H. (Joseph Herbert), 1924-
Publicado: (1988)

Editorial: Shaping with data: Using pharmacoepidemiology to shape pharmaceutical policy and clinical decision-making
por: Tadrous, Mina, et al.
Publicado: (2022)

An Integrative Genomic and Epigenomic Approach for the Study of Transcriptional Regulation
por: Figueroa, Maria E., et al.
Publicado: (2008)

An Efficient Approach to Screening Epigenome-Wide Data
por: Ray, Meredith A., et al.
Publicado: (2016)

Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study
por: Mendelson, Michael M., et al.
Publicado: (2018)

Repurposing of Antibiotics: Sense or Non-sense
por: Talat, Absar, et al.
Publicado: (2022)

Making Sense of the Big Picture: Data Linkage and Integration in the Era of Big Data
por: Chang, Hyejung
Publicado: (2018)

Editorial: Functional screening for cancer drug discovery: from experimental approaches to data integration
por: Zhou, Kecheng, et al.
Publicado: (2023)

An integrative approach to uncover the components, mechanisms, and functions of traditional Chinese medicine prescriptions on male infertility
por: Bai, Xue, et al.
Publicado: (2022)

A Qualitative Modeling Approach for Whole Genome Prediction Using High-Throughput Toxicogenomics Data and Pathway-Based Validation
por: Haider, Saad, et al.
Publicado: (2018)

Editorial: Role of Health Economic Data in Policy Making and Reimbursement of New Medical Technologies
por: Jakovljevic, Mihajlo, et al.
Publicado: (2017)

BioWardrobe: an integrated platform for analysis of epigenomics and transcriptomics data
por: Kartashov, Andrey V., et al.
Publicado: (2015)

Integrated Metabolomics and Network Pharmacology Approach to Explain Possible Action Mechanisms of Xin-Sheng-Hua Granule for Treating Anemia
por: Pang, Han-Qing, et al.
Publicado: (2018)

Making sense of data streams
por: SOKOL, Kacper Blazej
Publicado: (2014)

Making Sense of Data and Information
por: Elearn
Publicado: (2013)

An approach to data collection in compassionate use/managed access
por: Sarp, Séverine, et al.
Publicado: (2022)

Using real-world data for supporting regulatory decision making: Comparison of cardiovascular and safety outcomes of an empagliflozin randomized clinical trial versus real-world data
por: Jang, Ha Young, et al.
Publicado: (2022)

Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome
por: Tak, Yu Gyoung, et al.
Publicado: (2015)

Bookmarking the epigenome by retrovirus integration
por: Senigl, Filip, et al.
Publicado: (2011)

Integrating epigenomics into pharmacogenomic studies
por: Zhang, Wei, et al.
Publicado: (2008)

Multi-Omics Integration in a Twin Cohort and Predictive Modeling of Blood Pressure Values
por: Drouard, Gabin, et al.
Publicado: (2022)

Reviewing Data Integrated for PBPK Model Development to Predict Metabolic Drug-Drug Interactions: Shifting Perspectives and Emerging Trends
por: Abouir, Kenza, et al.
Publicado: (2021)

Cryptotanshinone Is a Intervention for ER-Positive Breast Cancer: An Integrated Approach to the Study of Natural Product Intervention Mechanisms
por: Li, Huayao, et al.
Publicado: (2021)

Probiotics-Based Treatment as an Integral Approach for Alcohol Use Disorder in Alcoholic Liver Disease
por: Fuenzalida, Catalina, et al.
Publicado: (2021)

MESIA: multi-epigenome sample integration approach for precise peak calling
por: Park, Seung Gwa, et al.
Publicado: (2023)

Fisetin: An Integrated Approach to Identify a Strategy Promoting Osteogenesis
por: Dalle Carbonare, Luca, et al.
Publicado: (2022)

Integrative analysis of genomic, epigenomic and transcriptomic data identified molecular subtypes of esophageal carcinoma
por: Ma, Mingyang, et al.
Publicado: (2021)

DBTSS as an integrative platform for transcriptome, epigenome and genome sequence variation data
por: Suzuki, Ayako, et al.
Publicado: (2014)

Integrative computational epigenomics to build data-driven gene regulation hypotheses
por: Chen, Tyrone, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hlun32j2htekn532n965cn8qcl