Cargando…

TDP-43 proteinopathy in Theiler’s murine encephalomyelitis virus infection

TDP-43, an RNA-binding protein that is primarily nuclear and important in splicing and RNA metabolism, is mislocalized from the nucleus to the cytoplasm of neural cells in amyotrophic lateral sclerosis (ALS), and contributes to disease. We sought to investigate whether TDP-43 is mislocalized in infe...

Descripción completa

Detalles Bibliográficos
Autores principales: Masaki, Katsuhisa, Sonobe, Yoshifumi, Ghadge, Ghanashyam, Pytel, Peter, Roos, Raymond P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390522/
https://www.ncbi.nlm.nih.gov/pubmed/30742696
http://dx.doi.org/10.1371/journal.ppat.1007574