Differences in expression rather than methylation at placenta-specific imprinted loci is associated with intrauterine growth restriction

BACKGROUND: Genome-wide studies have begun to link subtle variations in both allelic DNA methylation and parent-of-origin genetic effects with early development. Numerous reports have highlighted that the placenta plays a critical role in coordinating fetal growth, with many key functions regulated...

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Detalles Bibliográficos
Autores principales: Monteagudo-Sánchez, Ana, Sánchez-Delgado, Marta, Mora, Jose Ramon Hernandez, Santamaría, Nuria Tubío, Gratacós, Eduard, Esteller, Manel, de Heredia, Miguel López, Nunes, Virgina, Choux, Cecile, Fauque, Patricia, de Nanclares, Guiomar Perez, Anton, Lauren, Elovitz, Michal A., Iglesias-Platas, Isabel, Monk, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390544/
https://www.ncbi.nlm.nih.gov/pubmed/30808399
http://dx.doi.org/10.1186/s13148-019-0630-4

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