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Combination treatment with hypofractionated radiotherapy plus IL-2/anti-IL-2 complexes and its theranostic evaluation

BACKGROUND: Immunogenic radiotherapy (RT) can act synergistically with immune checkpoint blockers (ICBs). However, alternatives are needed for non-responding patients and those with pre-existing or ICB-induced autoimmune symptoms. Combination of RT with IL-2 could be an alternative. But IL-2 has a s...

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Detalles Bibliográficos
Autores principales: Jing, Hua, Hettich, Michael, Gaedicke, Simone, Firat, Elke, Bartholomä, Mark, Niedermann, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390578/
https://www.ncbi.nlm.nih.gov/pubmed/30808414
http://dx.doi.org/10.1186/s40425-019-0537-9