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Tetramethylpyrazine exerts a protective effect against injury from acute myocardial ischemia by regulating the PI3K/Akt/GSK-3β signaling pathway

OBJECTIVE: We investigated the protective effect of tetramethylpyrazine (TMP) on injury related to acute myocardial ischemia (AMI) induced by isoproterenol (ISO). MATERIALS AND METHODS: Rats were randomly assigned to five groups: control, ISO, ISO + propranolol (10 mg/kg), ISO + TMP (10 mg/kg) and I...

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Detalles Bibliográficos
Autores principales: Yang, Qing, Huang, Dan Dan, Li, Da Guang, Chen, Bo, Zhang, Ling Min, Yuan, Cui Ling, Huang, Hong Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390582/
https://www.ncbi.nlm.nih.gov/pubmed/30858867
http://dx.doi.org/10.1186/s11658-019-0141-5