Increased intratumoral mast cells foster immune suppression and gastric cancer progression through TNF-α-PD-L1 pathway

BACKGROUND: Mast cells are prominent components of solid tumors and exhibit distinct phenotypes in different tumor microenvironments. However, the nature, regulation, function, and clinical relevance of mast cells in human gastric cancer (GC) are presently unknown. METHODS: Flow cytometry analyses w...

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Detalles Bibliográficos
Autores principales: Lv, Yipin, Zhao, Yongliang, Wang, Xianhua, Chen, Na, Mao, Fangyuan, Teng, Yongsheng, Wang, Tingting, Peng, Liusheng, Zhang, Jinyu, Cheng, Ping, Liu, Yugang, Kong, Hui, Chen, Weisan, Hao, Chuanjie, Han, Bin, Ma, Qiang, Zou, Quanming, Chen, Jun, Zhuang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390584/
https://www.ncbi.nlm.nih.gov/pubmed/30808413
http://dx.doi.org/10.1186/s40425-019-0530-3

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