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High prevalence of protein tyrosine phosphatase non-receptor N22 gene functional variant R620W in systemic lupus erythematosus patients from Kuwait: implications for disease susceptibility

BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease which involves the loss of self-tolerance with hyperactivation of autoreactive T- and B-cells. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) encodes for lymphoid specific phosphatase (LYP) which is a ke...

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Detalles Bibliográficos
Autores principales:	Al-Awadhi, Adel M., Haider, Mohammad Z., Sukumaran, Jalaja, Balakrishnan, Sowmya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390595/ https://www.ncbi.nlm.nih.gov/pubmed/30886958 http://dx.doi.org/10.1186/s41927-018-0015-x

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