Laquinimod, a prototypic quinoline-3-carboxamide and aryl hydrocarbon receptor agonist, utilizes a CD155-mediated natural killer/dendritic cell interaction to suppress CNS autoimmunity

BACKGROUND: Quinoline-3-carboxamides, such as laquinimod, ameliorate CNS autoimmunity in patients and reduce tumor cell metastasis experimentally. Previous studies have focused on the immunomodulatory effect of laquinimod on myeloid cells. The data contained herein suggest that quinoline-3-carboxami...

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Detalles Bibliográficos
Autores principales: Ott, Martina, Avendaño-Guzmán, Erika, Ullrich, Evelyn, Dreyer, Carolin, Strauss, Judith, Harden, Markus, Schön, Margarete, Schön, Michael P., Bernhardt, Günter, Stadelmann, Christine, Wegner, Christiane, Brück, Wolfgang, Nessler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390632/
https://www.ncbi.nlm.nih.gov/pubmed/30808363
http://dx.doi.org/10.1186/s12974-019-1437-0

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