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Human 3D Gastrointestinal Microtissue Barrier Function As a Predictor of Drug-Induced Diarrhea

Drug-induced gastrointestinal toxicities (GITs) rank among the most common clinical side effects. Preclinical efforts to reduce incidence are limited by inadequate predictivity of in vitro assays. Recent breakthroughs in in vitro culture methods support intestinal stem cell maintenance and continual...

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Detalles Bibliográficos
Autores principales:	Peters, Matthew F, Landry, Tim, Pin, Carmen, Maratea, Kim, Dick, Cortni, Wagoner, Matthew P, Choy, Allison L, Barthlow, Herb, Snow, Deb, Stevens, Zachary, Armento, Alex, Scott, Clay W, Ayehunie, Seyoum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	3d GI Models for Predicting Drug-Induced Diarrhea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390652/ https://www.ncbi.nlm.nih.gov/pubmed/30364994 http://dx.doi.org/10.1093/toxsci/kfy268

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