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Empagliflozin Improves Diastolic Function in a Nondiabetic Rodent Model of Heart Failure With Preserved Ejection Fraction

Recent studies send an unambiguous signal that the class of agents known as sodium-glucose–linked co-transporter-2 inhibitors (SGLT2i) prevent heart failure hospitalization in patients with type 2 diabetes. However, the mechanisms remain unclear. Herein the authors utilize a rodent model of heart fa...

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Detalles Bibliográficos
Autores principales: Connelly, Kim A., Zhang, Yanling, Visram, Aylin, Advani, Andrew, Batchu, Sri N., Desjardins, Jean-François, Thai, Kerri, Gilbert, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390677/
https://www.ncbi.nlm.nih.gov/pubmed/30847416
http://dx.doi.org/10.1016/j.jacbts.2018.11.010