Cargando…

Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells

Adipose-derived mesenchymal stem cells (ADSCs) show considerable promise for clinical applications in regenerative medicine. We performed a large-scale single-cell transcriptomic sequencing of 24,358 cultured human ADSCs from three donors. We provide a high-quality dataset, which would be a valuable...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xuanyu, Xiang, Qinqin, Xu, Fen, Huang, Jiuzuo, Yu, Nanze, Zhang, Qixu, Long, Xiao, Zhou, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390702/
https://www.ncbi.nlm.nih.gov/pubmed/30806636
http://dx.doi.org/10.1038/sdata.2019.31
Descripción
Sumario:Adipose-derived mesenchymal stem cells (ADSCs) show considerable promise for clinical applications in regenerative medicine. We performed a large-scale single-cell transcriptomic sequencing of 24,358 cultured human ADSCs from three donors. We provide a high-quality dataset, which would be a valuable resource for dissecting the intrapopulation heterogeneity of cultured ADSCs as well as interrogating lineage priming patterns for any interested lineages at single-cell resolution.