Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells

Adipose-derived mesenchymal stem cells (ADSCs) show considerable promise for clinical applications in regenerative medicine. We performed a large-scale single-cell transcriptomic sequencing of 24,358 cultured human ADSCs from three donors. We provide a high-quality dataset, which would be a valuable...

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Detalles Bibliográficos
Autores principales: Liu, Xuanyu, Xiang, Qinqin, Xu, Fen, Huang, Jiuzuo, Yu, Nanze, Zhang, Qixu, Long, Xiao, Zhou, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2019
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390702/
https://www.ncbi.nlm.nih.gov/pubmed/30806636
http://dx.doi.org/10.1038/sdata.2019.31
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author Liu, Xuanyu
Xiang, Qinqin
Xu, Fen
Huang, Jiuzuo
Yu, Nanze
Zhang, Qixu
Long, Xiao
Zhou, Zhou
author_facet Liu, Xuanyu
Xiang, Qinqin
Xu, Fen
Huang, Jiuzuo
Yu, Nanze
Zhang, Qixu
Long, Xiao
Zhou, Zhou
author_sort Liu, Xuanyu
collection PubMed
description Adipose-derived mesenchymal stem cells (ADSCs) show considerable promise for clinical applications in regenerative medicine. We performed a large-scale single-cell transcriptomic sequencing of 24,358 cultured human ADSCs from three donors. We provide a high-quality dataset, which would be a valuable resource for dissecting the intrapopulation heterogeneity of cultured ADSCs as well as interrogating lineage priming patterns for any interested lineages at single-cell resolution.
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spelling pubmed-63907022019-02-27 Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells Liu, Xuanyu Xiang, Qinqin Xu, Fen Huang, Jiuzuo Yu, Nanze Zhang, Qixu Long, Xiao Zhou, Zhou Sci Data Data Descriptor Adipose-derived mesenchymal stem cells (ADSCs) show considerable promise for clinical applications in regenerative medicine. We performed a large-scale single-cell transcriptomic sequencing of 24,358 cultured human ADSCs from three donors. We provide a high-quality dataset, which would be a valuable resource for dissecting the intrapopulation heterogeneity of cultured ADSCs as well as interrogating lineage priming patterns for any interested lineages at single-cell resolution. Nature Publishing Group 2019-02-26 /pmc/articles/PMC6390702/ /pubmed/30806636 http://dx.doi.org/10.1038/sdata.2019.31 Text en Copyright © 2019, The Author(s) http://creativecommons.org/licenses/by/4.0/ Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the metadata files made available in this article.
spellingShingle Data Descriptor
Liu, Xuanyu
Xiang, Qinqin
Xu, Fen
Huang, Jiuzuo
Yu, Nanze
Zhang, Qixu
Long, Xiao
Zhou, Zhou
Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells
title Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells
title_full Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells
title_fullStr Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells
title_full_unstemmed Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells
title_short Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells
title_sort single-cell rna-seq of cultured human adipose-derived mesenchymal stem cells
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390702/
https://www.ncbi.nlm.nih.gov/pubmed/30806636
http://dx.doi.org/10.1038/sdata.2019.31
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