Prospective Whole-Genome Sequencing in Tuberculosis Outbreak Investigation, France, 2017–2018

During June 2017–April 2018, active tuberculosis with Beijing SIT1 isolates was diagnosed in 14 persons living in 4 distant cities in France. Whole-genome sequencing indicated that these patients belonged to a single transmission chain. Whole-genome sequencing–based laboratory investigations enabled...

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Detalles Bibliográficos
Autores principales: Genestet, Charlotte, Tatai, Caroline, Berland, Jean-Luc, Claude, Jean-Baptiste, Westeel, Emilie, Hodille, Elisabeth, Fredenucci, Isabelle, Rasigade, Jean-Philippe, Ponsoda, Michael, Jacomo, Véronique, Vachée, Anne, Gaudart, Alice, Gaillard, Jean-Louis, Roux, Anne-Laure, Ader, Florence, Tararbit, Karim, Terpant, Garance, Bryant, Juliet E., Lina, Gérard, Dumitrescu, Oana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390740/
https://www.ncbi.nlm.nih.gov/pubmed/30789329
http://dx.doi.org/10.3201/eid2503.181124
Descripción
Sumario:During June 2017–April 2018, active tuberculosis with Beijing SIT1 isolates was diagnosed in 14 persons living in 4 distant cities in France. Whole-genome sequencing indicated that these patients belonged to a single transmission chain. Whole-genome sequencing–based laboratory investigations enabled prompt tracing of linked cases to improve tuberculosis control.

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