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Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA

We evaluated enterovirus D68 seroprevalence in Kansas City, Missouri, USA, from samples obtained during 2012–2013. Neutralizing antibodies against Fermon and the dominant 2014 Missouri isolate were universally detected. Titers increased with age. Widespread circulation of enterovirus D68 occurred be...

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Autores principales: Harrison, Christopher J., Weldon, William C., Pahud, Barbara A., Jackson, Mary Anne, Oberste, M. Steven, Selvarangan, Rangaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390745/
https://www.ncbi.nlm.nih.gov/pubmed/30789123
http://dx.doi.org/10.3201/eid2503.180960
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author Harrison, Christopher J.
Weldon, William C.
Pahud, Barbara A.
Jackson, Mary Anne
Oberste, M. Steven
Selvarangan, Rangaraj
author_facet Harrison, Christopher J.
Weldon, William C.
Pahud, Barbara A.
Jackson, Mary Anne
Oberste, M. Steven
Selvarangan, Rangaraj
author_sort Harrison, Christopher J.
collection PubMed
description We evaluated enterovirus D68 seroprevalence in Kansas City, Missouri, USA, from samples obtained during 2012–2013. Neutralizing antibodies against Fermon and the dominant 2014 Missouri isolate were universally detected. Titers increased with age. Widespread circulation of enterovirus D68 occurred before the 2014 outbreak. Research is needed to determine a surrogate of protection.
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spelling pubmed-63907452019-03-06 Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA Harrison, Christopher J. Weldon, William C. Pahud, Barbara A. Jackson, Mary Anne Oberste, M. Steven Selvarangan, Rangaraj Emerg Infect Dis Dispatch We evaluated enterovirus D68 seroprevalence in Kansas City, Missouri, USA, from samples obtained during 2012–2013. Neutralizing antibodies against Fermon and the dominant 2014 Missouri isolate were universally detected. Titers increased with age. Widespread circulation of enterovirus D68 occurred before the 2014 outbreak. Research is needed to determine a surrogate of protection. Centers for Disease Control and Prevention 2019-03 /pmc/articles/PMC6390745/ /pubmed/30789123 http://dx.doi.org/10.3201/eid2503.180960 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Harrison, Christopher J.
Weldon, William C.
Pahud, Barbara A.
Jackson, Mary Anne
Oberste, M. Steven
Selvarangan, Rangaraj
Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA
title Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA
title_full Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA
title_fullStr Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA
title_full_unstemmed Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA
title_short Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA
title_sort neutralizing antibody against enterovirus d68 in children and adults before 2014 outbreak, kansas city, missouri, usa
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390745/
https://www.ncbi.nlm.nih.gov/pubmed/30789123
http://dx.doi.org/10.3201/eid2503.180960
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