Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia

A retrospective population-based molecular epidemiologic study of multidrug-resistant Mycobacterium tuberculosis complex strains in Serbia (2008–2014) revealed an outbreak of TUR genotype strains in a psychiatric hospital starting around 1990. Drug unavailability, poor infection control, and schizop...

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Autores principales: Arandjelović, Irena, Merker, Matthias, Richter, Elvira, Kohl, Thomas A., Savić, Branislava, Soldatović, Ivan, Wirth, Thierry, Vuković, Dragana, Niemann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390760/
https://www.ncbi.nlm.nih.gov/pubmed/30789133
http://dx.doi.org/10.3201/eid2503.181220
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author Arandjelović, Irena
Merker, Matthias
Richter, Elvira
Kohl, Thomas A.
Savić, Branislava
Soldatović, Ivan
Wirth, Thierry
Vuković, Dragana
Niemann, Stefan
author_facet Arandjelović, Irena
Merker, Matthias
Richter, Elvira
Kohl, Thomas A.
Savić, Branislava
Soldatović, Ivan
Wirth, Thierry
Vuković, Dragana
Niemann, Stefan
author_sort Arandjelović, Irena
collection PubMed
description A retrospective population-based molecular epidemiologic study of multidrug-resistant Mycobacterium tuberculosis complex strains in Serbia (2008–2014) revealed an outbreak of TUR genotype strains in a psychiatric hospital starting around 1990. Drug unavailability, poor infection control, and schizophrenia likely fueled acquisition of additional resistance and bacterial fitness–related mutations over 2 decades.
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spelling pubmed-63907602019-03-06 Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia Arandjelović, Irena Merker, Matthias Richter, Elvira Kohl, Thomas A. Savić, Branislava Soldatović, Ivan Wirth, Thierry Vuković, Dragana Niemann, Stefan Emerg Infect Dis Dispatch A retrospective population-based molecular epidemiologic study of multidrug-resistant Mycobacterium tuberculosis complex strains in Serbia (2008–2014) revealed an outbreak of TUR genotype strains in a psychiatric hospital starting around 1990. Drug unavailability, poor infection control, and schizophrenia likely fueled acquisition of additional resistance and bacterial fitness–related mutations over 2 decades. Centers for Disease Control and Prevention 2019-03 /pmc/articles/PMC6390760/ /pubmed/30789133 http://dx.doi.org/10.3201/eid2503.181220 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Arandjelović, Irena
Merker, Matthias
Richter, Elvira
Kohl, Thomas A.
Savić, Branislava
Soldatović, Ivan
Wirth, Thierry
Vuković, Dragana
Niemann, Stefan
Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia
title Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia
title_full Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia
title_fullStr Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia
title_full_unstemmed Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia
title_short Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia
title_sort longitudinal outbreak of multidrug-resistant tuberculosis in a hospital setting, serbia
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390760/
https://www.ncbi.nlm.nih.gov/pubmed/30789133
http://dx.doi.org/10.3201/eid2503.181220
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