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N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes
The discovery of significant amounts of metabolically active brown adipose tissue (BAT) in adult humans renders it a promising target for anti-obesity therapies by inducing weight loss through increased energy expenditure. The components of the N-acetylaspartate (NAA) pathway are highly abundant in...
Autores principales: | Huber, Katharina, Hofer, Dina C., Trefely, Sophie, Pelzmann, Helmut J., Madreiter-Sokolowski, Corina, Duta-Mare, Madalina, Schlager, Stefanie, Trausinger, Gert, Stryeck, Sarah, Graier, Wolfgang F., Kolb, Dagmar, Magnes, Christoph, Snyder, Nathaniel W., Prokesch, Andreas, Kratky, Dagmar, Madl, Tobias, Wellen, Kathryn E., Bogner-Strauss, Juliane G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390944/ https://www.ncbi.nlm.nih.gov/pubmed/30595160 http://dx.doi.org/10.1016/j.bbamcr.2018.08.017 |
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