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Idarucizumab in High-risk Thoracic Surgery

Direct oral anticoagulants have suggested a favorable profile compared with vitamin K antagonists. However, the lack of treatment to reverse the effect of direct oral anticoagulants has limited its use in some patients who require rapid reversal of anticoagulation, as those included in the transplan...

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Autores principales: López-Vilella, R., Sanz-Sánchez, J., Sánchez-Lázaro, I., Marques-Sule, E., Rueda-Soriano, J., Almenar-Bonet, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Organ Transplantation Institute 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390979/
https://www.ncbi.nlm.nih.gov/pubmed/30834094
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author López-Vilella, R.
Sanz-Sánchez, J.
Sánchez-Lázaro, I.
Marques-Sule, E.
Rueda-Soriano, J.
Almenar-Bonet, L.
author_facet López-Vilella, R.
Sanz-Sánchez, J.
Sánchez-Lázaro, I.
Marques-Sule, E.
Rueda-Soriano, J.
Almenar-Bonet, L.
author_sort López-Vilella, R.
collection PubMed
description Direct oral anticoagulants have suggested a favorable profile compared with vitamin K antagonists. However, the lack of treatment to reverse the effect of direct oral anticoagulants has limited its use in some patients who require rapid reversal of anticoagulation, as those included in the transplant waiting list. Idarucizumab is a recently approved drug to reverse the anticoagulant effect of dabigatran. However, the clinical experience when using this drug is scarce. Herein, we present a clinical case on anticoagulation reversal with idarucizumab to perform heart and lung transplantation in a patient with Eisenmenger syndrome.
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spelling pubmed-63909792019-03-04 Idarucizumab in High-risk Thoracic Surgery López-Vilella, R. Sanz-Sánchez, J. Sánchez-Lázaro, I. Marques-Sule, E. Rueda-Soriano, J. Almenar-Bonet, L. Int J Organ Transplant Med Case Report Direct oral anticoagulants have suggested a favorable profile compared with vitamin K antagonists. However, the lack of treatment to reverse the effect of direct oral anticoagulants has limited its use in some patients who require rapid reversal of anticoagulation, as those included in the transplant waiting list. Idarucizumab is a recently approved drug to reverse the anticoagulant effect of dabigatran. However, the clinical experience when using this drug is scarce. Herein, we present a clinical case on anticoagulation reversal with idarucizumab to perform heart and lung transplantation in a patient with Eisenmenger syndrome. Avicenna Organ Transplantation Institute 2018 2018-05-01 /pmc/articles/PMC6390979/ /pubmed/30834094 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
López-Vilella, R.
Sanz-Sánchez, J.
Sánchez-Lázaro, I.
Marques-Sule, E.
Rueda-Soriano, J.
Almenar-Bonet, L.
Idarucizumab in High-risk Thoracic Surgery
title Idarucizumab in High-risk Thoracic Surgery
title_full Idarucizumab in High-risk Thoracic Surgery
title_fullStr Idarucizumab in High-risk Thoracic Surgery
title_full_unstemmed Idarucizumab in High-risk Thoracic Surgery
title_short Idarucizumab in High-risk Thoracic Surgery
title_sort idarucizumab in high-risk thoracic surgery
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390979/
https://www.ncbi.nlm.nih.gov/pubmed/30834094
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