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Idarucizumab in High-risk Thoracic Surgery
Direct oral anticoagulants have suggested a favorable profile compared with vitamin K antagonists. However, the lack of treatment to reverse the effect of direct oral anticoagulants has limited its use in some patients who require rapid reversal of anticoagulation, as those included in the transplan...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Avicenna Organ Transplantation Institute
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390979/ https://www.ncbi.nlm.nih.gov/pubmed/30834094 |
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author | López-Vilella, R. Sanz-Sánchez, J. Sánchez-Lázaro, I. Marques-Sule, E. Rueda-Soriano, J. Almenar-Bonet, L. |
author_facet | López-Vilella, R. Sanz-Sánchez, J. Sánchez-Lázaro, I. Marques-Sule, E. Rueda-Soriano, J. Almenar-Bonet, L. |
author_sort | López-Vilella, R. |
collection | PubMed |
description | Direct oral anticoagulants have suggested a favorable profile compared with vitamin K antagonists. However, the lack of treatment to reverse the effect of direct oral anticoagulants has limited its use in some patients who require rapid reversal of anticoagulation, as those included in the transplant waiting list. Idarucizumab is a recently approved drug to reverse the anticoagulant effect of dabigatran. However, the clinical experience when using this drug is scarce. Herein, we present a clinical case on anticoagulation reversal with idarucizumab to perform heart and lung transplantation in a patient with Eisenmenger syndrome. |
format | Online Article Text |
id | pubmed-6390979 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Avicenna Organ Transplantation Institute |
record_format | MEDLINE/PubMed |
spelling | pubmed-63909792019-03-04 Idarucizumab in High-risk Thoracic Surgery López-Vilella, R. Sanz-Sánchez, J. Sánchez-Lázaro, I. Marques-Sule, E. Rueda-Soriano, J. Almenar-Bonet, L. Int J Organ Transplant Med Case Report Direct oral anticoagulants have suggested a favorable profile compared with vitamin K antagonists. However, the lack of treatment to reverse the effect of direct oral anticoagulants has limited its use in some patients who require rapid reversal of anticoagulation, as those included in the transplant waiting list. Idarucizumab is a recently approved drug to reverse the anticoagulant effect of dabigatran. However, the clinical experience when using this drug is scarce. Herein, we present a clinical case on anticoagulation reversal with idarucizumab to perform heart and lung transplantation in a patient with Eisenmenger syndrome. Avicenna Organ Transplantation Institute 2018 2018-05-01 /pmc/articles/PMC6390979/ /pubmed/30834094 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report López-Vilella, R. Sanz-Sánchez, J. Sánchez-Lázaro, I. Marques-Sule, E. Rueda-Soriano, J. Almenar-Bonet, L. Idarucizumab in High-risk Thoracic Surgery |
title | Idarucizumab in High-risk Thoracic Surgery |
title_full | Idarucizumab in High-risk Thoracic Surgery |
title_fullStr | Idarucizumab in High-risk Thoracic Surgery |
title_full_unstemmed | Idarucizumab in High-risk Thoracic Surgery |
title_short | Idarucizumab in High-risk Thoracic Surgery |
title_sort | idarucizumab in high-risk thoracic surgery |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390979/ https://www.ncbi.nlm.nih.gov/pubmed/30834094 |
work_keys_str_mv | AT lopezvilellar idarucizumabinhighriskthoracicsurgery AT sanzsanchezj idarucizumabinhighriskthoracicsurgery AT sanchezlazaroi idarucizumabinhighriskthoracicsurgery AT marquessulee idarucizumabinhighriskthoracicsurgery AT ruedasorianoj idarucizumabinhighriskthoracicsurgery AT almenarbonetl idarucizumabinhighriskthoracicsurgery |