Disruption of the Caenorhabditis elegans Integrator complex triggers a non-conventional transcriptional mechanism beyond snRNA genes

Gene expression is generally regulated by recruitment of transcription factors and RNA polymerase II (RNAP II) to specific sequences in the gene promoter region. The Integrator complex mediates processing of small nuclear RNAs (snRNAs) as well as the initiation and release of paused RNAP II at speci...

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Detalles Bibliográficos
Autores principales: Gómez-Orte, Eva, Sáenz-Narciso, Beatriz, Zheleva, Angelina, Ezcurra, Begoña, de Toro, María, López, Rosario, Gastaca, Irene, Nilsen, Hilde, Sacristán, María P., Schnabel, Ralf, Cabello, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390993/
https://www.ncbi.nlm.nih.gov/pubmed/30807579
http://dx.doi.org/10.1371/journal.pgen.1007981

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