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The transcription factor NHR-8: A new target to increase ivermectin efficacy in nematodes

Resistance to the anthelmintic macrocyclic lactone ivermectin (IVM) has a great impact on the control of parasitic nematodes. The mechanisms by which nematodes adapt to IVM remain to be deciphered. We have identified NHR-8, a nuclear hormone receptor involved in the xenobiotic response in Caenorhabd...

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Detalles Bibliográficos
Autores principales:	Ménez, Cécile, Alberich, Mélanie, Courtot, Elise, Guegnard, Fabrice, Blanchard, Alexandra, Aguilaniu, Hugo, Lespine, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391013/ https://www.ncbi.nlm.nih.gov/pubmed/30759156 http://dx.doi.org/10.1371/journal.ppat.1007598

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