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miR-491-5p functions as a tumor suppressor by targeting IGF2 in colorectal cancer
BACKGROUND: Dysregulation of miRNAs is critically implicated in tumorigenesis, and aberrant expression of miR-491-5p has been reported to play a key role in initiation and progression of various cancers. However, the biological function and underlying mechanism of miR-491-5p in colorectal cancer (CR...
Autores principales: | Lu, Lei, Cai, Ming, Peng, Meixia, Wang, Fei, Zhai, Xiaofeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391127/ https://www.ncbi.nlm.nih.gov/pubmed/30863186 http://dx.doi.org/10.2147/CMAR.S183085 |
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