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A novel, self-assembled artificial cartilage–hydroxyapatite conjugate for combined articular cartilage and subchondral bone repair: histopathological analysis of cartilage tissue engineering in rat knee joints
PURPOSE: We previously created a self-assembled cartilage-like complex in vitro from only three cartilage components, hyaluronic acid (HA), aggrecan (AG) and type II collagen, without other materials such as cross-linking agents. Based on this self-organized AG/HA/collagen complex, we have created t...
Autores principales: | Kumai, Takanori, Yui, Naoko, Yatabe, Kanaka, Sasaki, Chizuko, Fujii, Ryoji, Takenaga, Mitsuko, Fujiya, Hiroto, Niki, Hisateru, Yudoh, Kazuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391143/ https://www.ncbi.nlm.nih.gov/pubmed/30863061 http://dx.doi.org/10.2147/IJN.S193963 |
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