Energy-dependent endocytosis is responsible for drug transcorneal penetration following the instillation of ophthalmic formulations containing indomethacin nanoparticles

PURPOSE: We previously found that ophthalmic formulations containing nanoparticles prepared by a bead mill method lead to an increase in bioavailability in comparison with traditional formulations (solution type). However, the transcorneal penetration pathway for ophthalmic formulations has not been...

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Detalles Bibliográficos
Autores principales: Nagai, Noriaki, Ogata, Fumihiko, Otake, Hiroko, Nakazawa, Yosuke, Kawasaki, Naohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391158/
https://www.ncbi.nlm.nih.gov/pubmed/30863055
http://dx.doi.org/10.2147/IJN.S196681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391158/
https://www.ncbi.nlm.nih.gov/pubmed/30863055
http://dx.doi.org/10.2147/IJN.S196681

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