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Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development
PU.1 is an ETS-family transcription factor that plays a broad range of roles in hematopoiesis. A direct regulator of myeloid, dendritic-cell, and B cell functional programs, and a well-known antagonist of terminal erythroid cell differentiation, it is also expressed in the earliest stages of T-cell...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391351/ https://www.ncbi.nlm.nih.gov/pubmed/30842770 http://dx.doi.org/10.3389/fimmu.2019.00228 |