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Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development

PU.1 is an ETS-family transcription factor that plays a broad range of roles in hematopoiesis. A direct regulator of myeloid, dendritic-cell, and B cell functional programs, and a well-known antagonist of terminal erythroid cell differentiation, it is also expressed in the earliest stages of T-cell...

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Detalles Bibliográficos
Autores principales:	Rothenberg, Ellen V., Hosokawa, Hiroyuki, Ungerbäck, Jonas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391351/ https://www.ncbi.nlm.nih.gov/pubmed/30842770 http://dx.doi.org/10.3389/fimmu.2019.00228

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