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Glyoxylate cycle gene ICL1 is essential for the metabolic flexibility and virulence of Candida glabrata

The human fungal pathogen Candida glabrata appears to utilise unique stealth, evasion and persistence strategies in subverting the onslaught of host immune response during systemic infection. However, macrophages actively deprive the intracellular fungal pathogen of glucose, and therefore alternativ...

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Detalles Bibliográficos
Autores principales: Chew, Shu Yih, Ho, Kok Lian, Cheah, Yoke Kqueen, Ng, Tzu Shan, Sandai, Doblin, Brown, Alistair J. P., Than, Leslie Thian Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391369/
https://www.ncbi.nlm.nih.gov/pubmed/30808979
http://dx.doi.org/10.1038/s41598-019-39117-1