Cargando…

Silencing of spinal Trpv1 attenuates neuropathic pain in rats by inhibiting CAMKII expression and ERK2 phosphorylation

Accumulating evidence suggests a potential role of transient receptor potential vanilloid 1 (TRPV1) channels in inflammatory and cancer-related pain. However, the role of TRPV1 in the maintenance of neuropathic pain remains elusive. The current study investigated the effects of transient Trpv1 gene...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Shao-Hui, Lin, Jia-Piao, Huang, Ling-Er, Yang, Yan, Chen, Chao-Qin, Li, Na-Na, Su, Meng-Yun, Zhao, Xian, Zhu, Sheng-Mei, Yao, Yong-Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391380/ https://www.ncbi.nlm.nih.gov/pubmed/30808963 http://dx.doi.org/10.1038/s41598-019-39184-4

Ejemplares similares

Dexmedetomidine Attenuates Neuropathic Pain by Inhibiting P2X7R Expression and ERK Phosphorylation in Rats
por: Lin, Jia-Piao, et al.
Publicado: (2018)

LncRNA TINCR attenuates cardiac hypertrophy by epigenetically silencing CaMKII
por: Shao, Mingjing, et al.
Publicado: (2017)

Silencing of TRPV4-expressing sensory neurons attenuates temporomandibular disorders pain
por: Dias, Fabiana C, et al.
Publicado: (2023)

A TRPV4-dependent neuroimmune axis in the spinal cord promotes neuropathic pain
por: Hu, Xueming, et al.
Publicado: (2023)

Insular cortex stimulation alleviates neuropathic pain via ERK phosphorylation in neurons
por: Kim, Kyeongmin, et al.
Publicado: (2023)

Electroacupuncture Attenuates CFA-Induced Inflammatory Pain by Regulating CaMKII
por: Gu, Yixiao, et al.
Publicado: (2020)

Spinal SIRT1 Activation Attenuates Neuropathic Pain in Mice
por: Shao, Haijun, et al.
Publicado: (2014)

Systemic Sympathoexcitation Was Associated with Paraventricular Hypothalamic Phosphorylation of Synaptic CaMKIIα and MAPK/ErK
por: Ogundele, Olalekan M., et al.
Publicado: (2017)

HCN2 contributes to oxaliplatin-induced neuropathic pain through activation of the CaMKII/CREB cascade in spinal neurons
por: Liu, Xiaoyu, et al.
Publicado: (2018)

TRPV4 Role in Neuropathic Pain Mechanisms in Rodents
por: Rodrigues, Patrícia, et al.
Publicado: (2022)

The Role of CaMKII and ERK Signaling in Addiction
por: Jia, Wenbin, et al.
Publicado: (2021)

Baicalin prevents the up‐regulation of TRPV1 in dorsal root ganglion and attenuates chronic neuropathic pain
por: Wang, Zheyin, et al.
Publicado: (2020)

Oxytocin Relieves Neuropathic Pain Through GABA Release and Presynaptic TRPV1 Inhibition in Spinal Cord
por: Sun, Wuping, et al.
Publicado: (2018)

Phlomidis Radix Extract Alleviates Paclitaxel-Induced Neuropathic Pain by Modulating Spinal TRPV1 in Mice
por: Park, Keun-Tae, et al.
Publicado: (2023)

Primary sensory neuron-specific interference of TRPV1 signaling by adeno-associated virus-encoded TRPV1 peptide aptamer attenuates neuropathic pain
por: Xiang, Hongfei, et al.
Publicado: (2017)

Pirt Together with TRPV1 Is Involved in the Regulation of Neuropathic Pain
por: Wang, Changming, et al.
Publicado: (2018)

Electroacupuncture Alleviates Diabetic Neuropathic Pain and Downregulates p-PKC and TRPV1 in Dorsal Root Ganglions and Spinal Cord Dorsal Horn
por: Ma, Yi-qi, et al.
Publicado: (2023)

Expression of TRPV1 Channels after Nerve Injury Provides an Essential Delivery Tool for Neuropathic Pain Attenuation
por: Zakir, Hossain Md., et al.
Publicado: (2012)

PLGA-Curcumin Attenuates Opioid-Induced Hyperalgesia and Inhibits Spinal CaMKIIα
por: Hu, Xiaoyu, et al.
Publicado: (2016)

BHF177 Suppresses Diabetic Neuropathic Pain by Blocking PKC/CaMKII/ERK1/2/CREB Signaling Pathway through Activating GABA(B) Receptor
por: Liu, Boyu, et al.
Publicado: (2022)

Silencing of lncRNA PKIA-AS1 Attenuates Spinal Nerve Ligation-Induced Neuropathic Pain Through Epigenetic Downregulation of CDK6 Expression
por: Hu, Jian-Zhong, et al.
Publicado: (2019)

The analgesic effects of β-elemene in rats with neuropathic pain by inhibition of spinal astrocytic ERK activation
por: Ma, Li-Tian, et al.
Publicado: (2022)

Alpha‐lipoic acid downregulates TRPV1 receptor via NF‐κB and attenuates neuropathic pain in rats with diabetes
por: Zhang, Bing‐Yu, et al.
Publicado: (2020)

Upregulation of ERK phosphorylation in rat dorsal root ganglion neurons contributes to oxaliplatin-induced chronic neuropathic pain
por: Maruta, Toyoaki, et al.
Publicado: (2019)

Repeated electroacupuncture treatment attenuated hyperalgesia through suppression of spinal glial activation in chronic neuropathic pain rats
por: Wang, Jun-ying, et al.
Publicado: (2018)

Aberrant TRPV1 Expression in Heat Hyperalgesia Associated with Trigeminal Neuropathic Pain
por: Urano, Hiroko, et al.
Publicado: (2012)

Cardiac Protection of Valsartan on Juvenile Rats with Heart Failure by Inhibiting Activity of CaMKII via Attenuating Phosphorylation
por: Wu, Yao, et al.
Publicado: (2017)

Targeting the CaMKII/ERK Interaction in the Heart Prevents Cardiac Hypertrophy
por: Cipolletta, Ersilia, et al.
Publicado: (2015)

8-O-Acetyl Shanzhiside Methylester From Lamiophlomis Rotata Reduces Neuropathic Pain by Inhibiting the ERK/TNF-α Pathway in Spinal Astrocytes
por: Zhang, Wei, et al.
Publicado: (2018)

CaMKII Phosphorylation Regulates Synaptic Enrichment of Shank3
por: Jeong, Jaehoon, et al.
Publicado: (2021)

PKM2 is involved in neuropathic pain by regulating ERK and STAT3 activation in rat spinal cord
por: Wang, Binbin, et al.
Publicado: (2018)

Ablation of TRPV1+ Afferent Terminals by Capsaicin Mediates Long-Lasting Analgesia for Trigeminal Neuropathic Pain
por: Wang, Sheng, et al.
Publicado: (2020)

Fumagillin Attenuates Spinal Angiogenesis, Neuroinflammation, and Pain in Neuropathic Rats after Chronic Constriction Injury
por: Wen, Zhi-Hong, et al.
Publicado: (2021)

Pulsed radiofrequency attenuates diabetic neuropathic pain and suppresses formalin-evoked spinal glutamate release in rats
por: Huang, Yu-Hsin, et al.
Publicado: (2016)

Oral administration of curcumin attenuates visceral hyperalgesia through inhibiting phosphorylation of TRPV1 in rat model of ulcerative colitis
por: Yang, Mei, et al.
Publicado: (2017)

Identification of lncRNA expression profile in the spinal cord of mice following spinal nerve ligation-induced neuropathic pain
por: Jiang, Bao-Chun, et al.
Publicado: (2015)

TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice
por: Marrone, Maria Cristina, et al.
Publicado: (2017)

NMDA receptor-mediated CaMKII/ERK activation contributes to renal fibrosis
por: Zhou, Jingyi, et al.
Publicado: (2020)

Koumine Attenuates Neuroglia Activation and Inflammatory Response to Neuropathic Pain
por: Jin, Gui-Lin, et al.
Publicado: (2018)

Systemic Injection of Thalidomide Prevent and Attenuate Neuropathic Pain and Alleviate Neuroinflammatory Response in the Spinal Dorsal Horn
por: Xu, Hao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ftnsejk60hjkfq5t8di97caoek