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A reduced concentration of brain interstitial amino acids is associated with depression in subarachnoid hemorrhage patients

The amino-acids tryptophan, phenylalanine and tyrosine seem to play an important role in the pathophysiology of depressive disorders. We measured daily brain extracellular levels of these amino-acids using cerebral microdialysis (CMD) and high performance liquid chromatography in 26 consecutive suba...

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Detalles Bibliográficos
Autores principales: Kofler, Mario, Schiefecker, Alois Josef, Gaasch, Maxime, Sperner-Unterweger, Barbara, Fuchs, Dietmar, Beer, Ronny, Ferger, Boris, Rass, Verena, Hackl, Werner, Rhomberg, Paul, Pfausler, Bettina, Thomé, Claudius, Schmutzhard, Erich, Helbok, Raimund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391430/
https://www.ncbi.nlm.nih.gov/pubmed/30808966
http://dx.doi.org/10.1038/s41598-019-39569-5

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