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Extensive epigenomic integration of the glucocorticoid response in primary human monocytes and in vitro derived macrophages
Glucocorticoid receptor is a transcription factor that is ubiquitously expressed. Glucocorticoids are circadian steroids that regulate a wide range of bodily functions, including immunity. Here we report that synthetic glucocorticoids affect 1035 mRNAs in isolated healthy human blood monocytes but o...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391480/ https://www.ncbi.nlm.nih.gov/pubmed/30809020 http://dx.doi.org/10.1038/s41598-019-39395-9 |