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Deletion of Ripk3 Prevents Motor Neuron Death In Vitro but not In Vivo

Increasing evidence suggests that necroptosis, a form of programmed cell death (PCD), contributes to neurodegeneration in several disorders, including ALS. Supporting this view, investigations in both in vitro and in vivo models of ALS have implicated key molecular determinants of necroptosis in the...

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Detalles Bibliográficos
Autores principales:	Dermentzaki, Georgia, Politi, Kristin A., Lu, Lei, Mishra, Vartika, Pérez-Torres, Eduardo J., Sosunov, Alexander A., McKhann, Guy M., Lotti, Francesco, Shneider, Neil A., Przedborski, Serge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2019
Materias:	Negative Results
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391588/ https://www.ncbi.nlm.nih.gov/pubmed/30815534 http://dx.doi.org/10.1523/ENEURO.0308-18.2018

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