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Heart valve disease in elderly

The incidence of heart valve disease increases significantly with age. Degenerative abnormalities associated with severe aortic stenosis and mitral and tricuspid regurgitation are found in not less than 10% of the population aged ≥ 75 years. Surgical treatment has been considered for years to be the...

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Autor principal: Rostagno, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391621/
https://www.ncbi.nlm.nih.gov/pubmed/30820277
http://dx.doi.org/10.4330/wjc.v11.i2.71
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author Rostagno, Carlo
author_facet Rostagno, Carlo
author_sort Rostagno, Carlo
collection PubMed
description The incidence of heart valve disease increases significantly with age. Degenerative abnormalities associated with severe aortic stenosis and mitral and tricuspid regurgitation are found in not less than 10% of the population aged ≥ 75 years. Surgical treatment has been considered for years to be the treatment of choice. However, it was not uncommonly associated with high perioperative morbidity and mortality due to frequent comorbidities and overall frailty conditions of these patients. Conventional risk scores such as Society of Thoracic Surgeons and European System for Cardiac Operative Risk Evaluation may underestimate the risk of surgery in elderly patients, leading to inappropriate surgical indication. On the other hand, at least 30% of patients with severe conditions are left untreated due to prohibitive surgical risk. Interventional procedures, which are in continuous development, may be actually considered for high risk patients and, as recent results suggest, also for intermediate risk patients.
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spelling pubmed-63916212019-02-28 Heart valve disease in elderly Rostagno, Carlo World J Cardiol Minireviews The incidence of heart valve disease increases significantly with age. Degenerative abnormalities associated with severe aortic stenosis and mitral and tricuspid regurgitation are found in not less than 10% of the population aged ≥ 75 years. Surgical treatment has been considered for years to be the treatment of choice. However, it was not uncommonly associated with high perioperative morbidity and mortality due to frequent comorbidities and overall frailty conditions of these patients. Conventional risk scores such as Society of Thoracic Surgeons and European System for Cardiac Operative Risk Evaluation may underestimate the risk of surgery in elderly patients, leading to inappropriate surgical indication. On the other hand, at least 30% of patients with severe conditions are left untreated due to prohibitive surgical risk. Interventional procedures, which are in continuous development, may be actually considered for high risk patients and, as recent results suggest, also for intermediate risk patients. Baishideng Publishing Group Inc 2019-02-26 2019-02-26 /pmc/articles/PMC6391621/ /pubmed/30820277 http://dx.doi.org/10.4330/wjc.v11.i2.71 Text en ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Minireviews
Rostagno, Carlo
Heart valve disease in elderly
title Heart valve disease in elderly
title_full Heart valve disease in elderly
title_fullStr Heart valve disease in elderly
title_full_unstemmed Heart valve disease in elderly
title_short Heart valve disease in elderly
title_sort heart valve disease in elderly
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391621/
https://www.ncbi.nlm.nih.gov/pubmed/30820277
http://dx.doi.org/10.4330/wjc.v11.i2.71
work_keys_str_mv AT rostagnocarlo heartvalvediseaseinelderly