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FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I–induced DNA breakage and transcriptional stress

FUS (fused in sarcoma) plays a key role in several steps of RNA metabolism, and dominant mutations in this protein are associated with neurodegenerative diseases. Here, we show that FUS is a component of the cellular response to topoisomerase I (TOP1)–induced DNA breakage; relocalising to the nucleo...

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Detalles Bibliográficos
Autores principales:	Martinez-Macias, Maria Isabel, Moore, Duncan AQ, Green, Ryan L, Gomez-Herreros, Fernando, Naumann, Marcel, Hermann, Andreas, Van Damme, Philip, Hafezparast, Majid, Caldecott, Keith W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391683/ https://www.ncbi.nlm.nih.gov/pubmed/30808650 http://dx.doi.org/10.26508/lsa.201800222

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