Standard protocol for the total red blood cell Pig-a assay used in the interlaboratory trial organized by the Mammalian Mutagenicity Study Group of the Japanese Environmental Mutagen Society

The Pig-a assay, a promising tool for evaluating in vivo genotoxicity, is based on flow cytometric enumeration of red blood cells (RBCs) that are deficient in glycosylphosphatidylinositol anchor protein. Various approaches for measuring Pig-a mutant cells have been developed, particularly focusing o...

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Detalles Bibliográficos
Autores principales: Chikura, Satsuki, Kimoto, Takafumi, Itoh, Satoru, Sanada, Hisakazu, Muto, Shigeharu, Horibata, Katsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391751/
https://www.ncbi.nlm.nih.gov/pubmed/30858897
http://dx.doi.org/10.1186/s41021-019-0121-z

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