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Age Dependent Dysfunction of Mitochondrial and ROS Metabolism Induced by Mitonuclear Mismatch

Mitochondrial and nuclear genomes have to coevolve to ensure the proper functioning of the different mitochondrial complexes that are assembled from peptides encoded by both genomes. Mismatch between these genomes is believed to be strongly selected against due to the consequent impairments of mitoc...

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Detalles Bibliográficos
Autores principales: Pichaud, Nicolas, Bérubé, Roxanne, Côté, Geneviève, Belzile, Claude, Dufresne, France, Morrow, Geneviève, Tanguay, Robert M., Rand, David M., Blier, Pierre U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391849/
https://www.ncbi.nlm.nih.gov/pubmed/30842791
http://dx.doi.org/10.3389/fgene.2019.00130