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Phosphatase Actin Regulator-1 (PHACTR-1) Knockdown Suppresses Cell Proliferation and Migration and Promotes Cell Apoptosis in the bEnd.3 Mouse Brain Capillary Endothelial Cell Line

BACKGROUND: The phosphatase actin regulator-1 (PHACTR-1) gene on chromosome 6 encodes an actin and protein phosphatase 1 (PP1) binding protein, Phactr-1, which is highly expressed in brain tissues. Phactr-1 expression is involved in physiological and pathological cerebral microvascular events. This...

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Detalles Bibliográficos
Autores principales: Jing, Yao, Zhang, Lin, Xu, Zhiming, Chen, Hao, Ju, Shiming, Ding, Jun, Guo, Yan, Tian, Hengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391858/
https://www.ncbi.nlm.nih.gov/pubmed/30772888
http://dx.doi.org/10.12659/MSM.912586