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LncRNAs GIHCG and SPINT1-AS1 Are Crucial Factors for Pan-Cancer Cells Sensitivity to Lapatinib

Lapatinib is a small molecule inhibitor of EGFR (HER1) and ERBB2 (HER2) receptors, which is used for treatment of advanced or metastatic breast cancer. To find the drug resistance mechanisms of treatment for EGFR/ERBB2 positive tumors, we analyzed the possible effects of lncRNAs. In this study, usin...

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Detalles Bibliográficos
Autores principales: Xiang, Zhen, Song, Shuzheng, Zhu, Zhenggang, Sun, Wenhong, Gifts, Jaron E., Sun, Sam, Li, Qiushi Shauna, Yu, Yingyan, Li, Keqin Kathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391897/
https://www.ncbi.nlm.nih.gov/pubmed/30842786
http://dx.doi.org/10.3389/fgene.2019.00025