A Novel, Drug Resistance-Independent, Fluorescence-Based Approach To Measure Mutation Rates in Microbial Pathogens

All evolutionary processes are underpinned by a cellular capacity to mutate DNA. To identify factors affecting mutagenesis, it is necessary to compare mutation rates between different strains and conditions. Drug resistance-based mutation reporters are used extensively to measure mutation rates, but...

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Detalles Bibliográficos
Autores principales: Shor, Erika, Schuyler, Jessica, Perlin, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391916/
https://www.ncbi.nlm.nih.gov/pubmed/30808701
http://dx.doi.org/10.1128/mBio.00120-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391916/
https://www.ncbi.nlm.nih.gov/pubmed/30808701
http://dx.doi.org/10.1128/mBio.00120-19

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