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HIV-1 Escape from Small-Molecule Antagonism of Vif

The HIV-1 accessory protein Vif, which counteracts the antiviral action of the DNA-editing cytidine deaminase APOBEC3G (A3G), is an attractive and yet unexploited therapeutic target. Vif reduces the virion incorporation of A3G by targeting the restriction factor for proteasomal degradation in the vi...

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Detalles Bibliográficos
Autores principales:	Sharkey, Mark, Sharova, Natalia, Mohammed, Idrees, Huff, Sarah E., Kummetha, Indrasena Reddy, Singh, Gatikrushna, Rana, Tariq M., Stevenson, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391917/ https://www.ncbi.nlm.nih.gov/pubmed/30808702 http://dx.doi.org/10.1128/mBio.00144-19

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