Cu and Hydroquinone for the Trifluoromethylation of Unprotected Phenols

Fluorination and trifluoromethylation are indispensable tools in the preparation of modern pharmaceuticals and APIs. Herein we present a concept for the introduction of a trifluoromethyl group into unprotected phenols employing catalytic copper(I) iodide and hydroquinone, tBuOOH, and the Langlois�...

Descripción completa

Detalles Bibliográficos
Autores principales: Pletz, Jakob, Koeberl, Christoph, Fuchs, Michael, Steiner, Oliver, Goessler, Walter, Kroutil, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391967/
https://www.ncbi.nlm.nih.gov/pubmed/30853852
http://dx.doi.org/10.1002/ejoc.201801111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391967/
https://www.ncbi.nlm.nih.gov/pubmed/30853852
http://dx.doi.org/10.1002/ejoc.201801111

Ejemplares similares