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Transcellular Spreading of Tau in Tauopathies

Tau, a microtubule‐associated protein playing a key role in a group of neurodegenerative diseases such as Alzheimer's disease, spreads throughout the brain, inducing pathology. A model akin to the spreading of prions has been raised owing to similar characteristics of inducing an abnormal prote...

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Detalles Bibliográficos
Autores principales: Demaegd, Koen, Schymkowitz, Joost, Rousseau, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391987/
https://www.ncbi.nlm.nih.gov/pubmed/30133080
http://dx.doi.org/10.1002/cbic.201800288