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Minor Isozymes Tailor Yeast Metabolism to Carbon Availability

Isozymes are enzymes that differ in sequence but catalyze the same chemical reactions. Despite their apparent redundancy, isozymes are often retained over evolutionary time, suggesting that they contribute to fitness. We developed an unsupervised computational method for identifying environmental co...

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Detalles Bibliográficos
Autores principales: Bradley, Patrick H., Gibney, Patrick A., Botstein, David, Troyanskaya, Olga G., Rabinowitz, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392091/
https://www.ncbi.nlm.nih.gov/pubmed/30834327
http://dx.doi.org/10.1128/mSystems.00170-18