Cargando…

Model-Based Assessment of the Role of Uneven Partitioning of Molecular Content on Heterogeneity and Regulation of Differentiation in CD8 T-Cell Immune Responses

Activation of naive CD8 T-cells can lead to the generation of multiple effector and memory subsets. Multiple parameters associated with activation conditions are involved in generating this diversity that is associated with heterogeneous molecular contents of activated cells. Although naive cell pol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Girel, Simon, Arpin, Christophe, Marvel, Jacqueline, Gandrillon, Olivier, Crauste, Fabien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392104/ https://www.ncbi.nlm.nih.gov/pubmed/30842771 http://dx.doi.org/10.3389/fimmu.2019.00230

Ejemplares similares

Modeling and characterization of inter-individual variability in CD8 T cell responses in mice
por: Audebert, Chloe, et al.
Publicado: (2021)

IL-2 sensitivity and exogenous IL-2 concentration gradient tune the productive contact duration of CD8(+) T cell-APC: a multiscale modeling study
por: Gao, Xuefeng, et al.
Publicado: (2016)

CD8 memory precursor cell generation is a continuous process
por: Todorov, Helena, et al.
Publicado: (2022)

Drugs modulating stochastic gene expression affect the erythroid differentiation process
por: Guillemin, Anissa, et al.
Publicado: (2019)

Calibration, Selection and Identifiability Analysis of a Mathematical Model of the in vitro Erythropoiesis in Normal and Perturbed Contexts
por: Duchesne, Ronan, et al.
Publicado: (2019)

Practical identifiability in the frame of nonlinear mixed effects models: the example of the in vitro erythropoiesis
por: Duchesne, Ronan, et al.
Publicado: (2021)

Heterogeneity of HBV-Specific CD8(+) T-Cell Failure: Implications for Immunotherapy
por: Heim, Kathrin, et al.
Publicado: (2019)

The development of CD8 T-cell exhaustion heterogeneity and the therapeutic potentials in cancer
por: Zhang, Junfeng, et al.
Publicado: (2023)

Divide and Conquer: Phenotypic and Temporal Heterogeneity Within CD8(+) T Cell Responses
por: Richard, Arianne C.
Publicado: (2022)

Immune signatures of protective spleen memory CD8 T cells
por: Brinza, Lilia, et al.
Publicado: (2016)

OVX836 Heptameric Nucleoprotein Vaccine Generates Lung Tissue-Resident Memory CD8+ T-Cells for Cross-Protection Against Influenza
por: Del Campo, Judith, et al.
Publicado: (2021)

The Concept of Evenness/Unevenness: Less Evenness or More Unevenness?
por: Gregorius, Hans-Rolf, et al.
Publicado: (2021)

An uneven pandemic
por: Vaughan, Adam
Publicado: (2020)

CD8αα Expression Marks Terminally Differentiated Human CD8+ T Cells Expanded in Chronic Viral Infection
por: Walker, L. J., et al.
Publicado: (2013)

Immune Checkpoint Function of CD85j in CD8 T Cell Differentiation and Aging
por: Gustafson, Claire E., et al.
Publicado: (2017)

Hypoxia Supports Differentiation of Terminally Exhausted CD8 T Cells
por: Bannoud, Nadia, et al.
Publicado: (2021)

Differential Expression of Immune Checkpoint Modulators on In Vitro Primed CD4(+) and CD8(+) T Cells
por: Sabins, Nina C., et al.
Publicado: (2016)

CD8+ T cell trajectory subtypes decode tumor heterogeneity and provide treatment recommendations for hepatocellular carcinoma
por: Liu, Long, et al.
Publicado: (2022)

Tle corepressors are differentially partitioned to instruct CD8(+) T cell lineage choice and identity
por: Xing, Shaojun, et al.
Publicado: (2018)

Transcriptional and Epigenetic Regulation of Effector and Memory CD8 T Cell Differentiation
por: Chen, Yao, et al.
Publicado: (2018)

Metabolic alterations impair differentiation and effector functions of CD8+ T cells
por: Bensussen, Antonio, et al.
Publicado: (2022)

CD4(+)CD8(+) T-Lymphocytes in Xenogeneic and Human Graft-versus-Host Disease
por: Alhaj Hussen, Kutaiba, et al.
Publicado: (2020)

Loss of CD96 Expression as a Marker of HIV-Specific CD8(+) T-Cell Differentiation and Dysfunction
por: Bunet, Rémi, et al.
Publicado: (2021)

Differential Role of “Signal 3” Inflammatory Cytokines in Regulating CD8 T Cell Expansion and Differentiation in vivo
por: Pham, Nhat-Long L., et al.
Publicado: (2011)

Defining the molecular blueprint that drives CD8(+) T cell differentiation in response to infection
por: Russ, Brendan E., et al.
Publicado: (2012)

CMV-Specific CD8 T Cell Differentiation and Localization: Implications for Adoptive Therapies
por: Smith, Corinne J., et al.
Publicado: (2016)

Metabolic Control of Epigenetics and Its Role in CD8(+) T Cell Differentiation and Function
por: Yerinde, Cansu, et al.
Publicado: (2019)

Transcriptome Profiling of Porcine Naïve, Intermediate and Terminally Differentiated CD8(+) T Cells
por: Lagumdzic, Emil, et al.
Publicado: (2022)

Human and Mouse CD8(+)CD25(+)FOXP3(+) Regulatory T Cells at Steady State and during Interleukin-2 Therapy
por: Churlaud, Guillaume, et al.
Publicado: (2015)

Notch controls effector CD8(+) T cell differentiation
por: Duval, Frédéric, et al.
Publicado: (2015)

Differential Requirement of Cd8 Enhancers E8(I) and E8(VI) in Cytotoxic Lineage T Cells and in Intestinal Intraepithelial Lymphocytes
por: Gülich, Alexandra Franziska, et al.
Publicado: (2019)

Resting Memory CD8(+) T Cells are Hyperreactive to Antigenic Challenge In Vitro
por: Pihlgren, Maria, et al.
Publicado: (1996)

CD40L Expression Allows CD8(+) T Cells to Promote Their Own Expansion and Differentiation through Dendritic Cells
por: Tay, Neil Q., et al.
Publicado: (2017)

Negative Regulation of Zap70 by Lck Forms the Mechanistic Basis of Differential Expression in CD4 and CD8 T Cells
por: Damen, Hassan, et al.
Publicado: (2022)

Role of PI3K/Akt signaling in memory CD8 T cell differentiation
por: Kim, Eui Ho, et al.
Publicado: (2013)

The smallest unit: effector and memory CD8(+) T cell differentiation on the single cell level
por: Buchholz, Veit R., et al.
Publicado: (2013)

Genealogy, Dendritic Cell Priming, and Differentiation of Tissue-Resident Memory CD8(+) T Cells
por: Enamorado, Michel, et al.
Publicado: (2018)

Differentiation and Function of Follicular CD8 T Cells During Human Immunodeficiency Virus Infection
por: Xiao, Minglu, et al.
Publicado: (2018)

Modulation of let-7 miRNAs controls the differentiation of effector CD8 T cells
por: Wells, Alexandria C, et al.
Publicado: (2017)

IL-12-Induced Immune Suppressive Deficit During CD8+ T-Cell Differentiation
por: Renavikar, Pranav S., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_09s6o06p62lc5328ondpcbtcj4