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A Mass‐Spectrometry‐Based Modelling Workflow for Accurate Prediction of IgG Antibody Conformations in the Gas Phase

Immunoglobulins are biomolecules involved in defence against foreign substances. Flexibility is key to their functional properties in relation to antigen binding and receptor interactions. We have developed an integrative strategy combining ion mobility mass spectrometry (IM‐MS) with molecular model...

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Detalles Bibliográficos
Autores principales:	Hansen, Kjetil, Lau, Andy M., Giles, Kevin, McDonnell, James M., Struwe, Weston B., Sutton, Brian J., Politis, Argyris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392142/ https://www.ncbi.nlm.nih.gov/pubmed/30408305 http://dx.doi.org/10.1002/anie.201812018

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