Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver

Physical activity promotes metabolic and cardiovascular health benefits that derive in part from the transcriptional responses to exercise that occur within skeletal muscle and other organs. There is interest in discovering a pharmacologic exercise mimetic that could imbue wellness and alleviate dis...

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Detalles Bibliográficos
Autores principales: Muise, Eric S., Guan, Hong-Ping, Liu, Jinqi, Nawrocki, Andrea R., Yang, Xiaodong, Wang, Chuanlin, Rodríguez, Carlos G., Zhou, Dan, Gorski, Judith N., Kurtz, Marc M., Feng, Danqing, Leavitt, Kenneth J., Wei, Lan, Wilkening, Robert R., Apgar, James M., Xu, Shiyao, Lu, Ku, Feng, Wen, Li, Ying, He, Huaibing, Previs, Stephen F., Shen, Xiaolan, van Heek, Margaret, Souza, Sandra C., Rosenbach, Mark J., Biftu, Tesfaye, Erion, Mark D., Kelley, David E., Kemp, Daniel M., Myers, Robert W., Sebhat, Iyassu K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392219/
https://www.ncbi.nlm.nih.gov/pubmed/30811418
http://dx.doi.org/10.1371/journal.pone.0211568

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