Effect of cyclical intermittent hypoxia on Ad5CMVCre induced solitary lung cancer progression and spontaneous metastases in the Kras(G12D+); p53(fl/fl); myristolated p110(fl/fl) ROSA-gfp mouse

BACKGROUND: Epidemiological data suggests that obstructive sleep apnea (OSA) is associated with increased cancer incidence and mortality. We investigate the effects of cyclical intermittent hypoxia (CIH), akin to the underlying pathophysiology of OSA, on lung cancer progression and metastatic profil...

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Detalles Bibliográficos
Autores principales: Guo, Xiaofeng, Liu, Yan, Kim, Jessica L., Kim, Emily Y., Kim, Edison Q., Jansen, Alexandria, Li, Katherine, Chan, May, Keenan, Brendan T., Conejo-Garcia, Jose, Lim, Diane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392281/
https://www.ncbi.nlm.nih.gov/pubmed/30811514
http://dx.doi.org/10.1371/journal.pone.0212930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392281/
https://www.ncbi.nlm.nih.gov/pubmed/30811514
http://dx.doi.org/10.1371/journal.pone.0212930

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