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Deletion of suppressor of cytokine signaling 3 (SOCS3) in muscle stem cells does not alter muscle regeneration in mice after injury
Muscles of older animals are more susceptible to injury and regenerate poorly, in part due to a persistent inflammatory response. The janus kinase (Jak)/signal transducer and activator of transcription (Stat) pathway mediates inflammatory signaling and is tightly regulated by the suppressor of cytok...
Autores principales: | Swiderski, Kristy, Caldow, Marissa K., Naim, Timur, Trieu, Jennifer, Chee, Annabel, Koopman, René, Lynch, Gordon S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392323/ https://www.ncbi.nlm.nih.gov/pubmed/30811469 http://dx.doi.org/10.1371/journal.pone.0212880 |
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