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Renal and vascular effects of kallikrein inhibition in a model of Lonomia obliqua venom-induced acute kidney injury
BACKGROUND: Lonomia obliqua venom is nephrotoxic and acute kidney injury (AKI) is the main cause of death among envenomed victims. Mechanism underlying L. obliqua-induced AKI involves renal hypoperfusion, inflammation, tubular necrosis and loss of glomerular filtration and tubular reabsorption capac...
Autores principales: | Berger, Markus, de Moraes, João Alfredo, Beys-da-Silva, Walter Orlando, Santi, Lucélia, Terraciano, Paula Barros, Driemeier, David, Cirne-Lima, Elizabeth Obino, Passos, Eduardo Pandolfi, Vieira, Maria Aparecida Ribeiro, Barja-Fidalgo, Thereza Christina, Guimarães, Jorge Almeida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392336/ https://www.ncbi.nlm.nih.gov/pubmed/30763408 http://dx.doi.org/10.1371/journal.pntd.0007197 |
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