EFHC1, implicated in juvenile myoclonic epilepsy, functions at the cilium and synapse to modulate dopamine signaling

Neurons throughout the mammalian brain possess non-motile cilia, organelles with varied functions in sensory physiology and cellular signaling. Yet, the roles of cilia in these neurons are poorly understood. To shed light into their functions, we studied EFHC1, an evolutionarily conserved protein re...

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Detalles Bibliográficos
Autores principales: Loucks, Catrina M, Park, Kwangjin, Walker, Denise S, McEwan, Andrea H, Timbers, Tiffany A, Ardiel, Evan L, Grundy, Laura J, Li, Chunmei, Johnson, Jacque-Lynne, Kennedy, Julie, Blacque, Oliver E, Schafer, William, Rankin, Catharine H, Leroux, Michel R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392500/
https://www.ncbi.nlm.nih.gov/pubmed/30810526
http://dx.doi.org/10.7554/eLife.37271

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