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Epidural versus intravenous steroids application following percutaneous endoscopic lumbar discectomy

Retrospectively study. The purpose of this study was to compare the effects of intraoperative epidural steroids and single dose intravenous steroids following a percutaneous endoscopic lumbar discectomy (PELD). Inflammatory irritation of dorsal root ganglia or sensory nerve roots may cause postopera...

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Autores principales: Hu, Annan, Gu, Xin, Guan, Xiaofei, Fan, Guoxin, He, Shisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392748/
https://www.ncbi.nlm.nih.gov/pubmed/29718884
http://dx.doi.org/10.1097/MD.0000000000010654
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author Hu, Annan
Gu, Xin
Guan, Xiaofei
Fan, Guoxin
He, Shisheng
author_facet Hu, Annan
Gu, Xin
Guan, Xiaofei
Fan, Guoxin
He, Shisheng
author_sort Hu, Annan
collection PubMed
description Retrospectively study. The purpose of this study was to compare the effects of intraoperative epidural steroids and single dose intravenous steroids following a percutaneous endoscopic lumbar discectomy (PELD). Inflammatory irritation of dorsal root ganglia or sensory nerve roots may cause postoperative pain. Epidural steroids have been applied after a lumbar discectomy for more than 20 years. Epidural steroid application after a PELD is easier to perform and safer because the operations are under observation of the scope. We retrospectively reviewed the medical records of patients with lumbar intervertebral disc herniation who had undergone transforaminal PELD at our department. There are 60 patients in epidural steroid group, intravenous steroid group, and control group, respectively. Visual analog scores (VAS) and the Oswestry Disability Index (ODI) were collected. Successful pain control is defined as 50% or more reduction in back and leg pain (VAS scores). VAS scores (back and leg) and ODI showed a significant decrease in all groups when comparing pre- and postoperatively. Epidural steroid group had a significant improvement in successful pain control compared with the control group at 2 weeks of follow-up. VAS scores (leg) in the epidural steroid group showed a significant decrease compared with the intravenous steroids group at 1, 3, and 7 days after the surgery, but this difference had no statistical significance at 1, 6, and 12 months of follow-up. All groups did not show a significant difference in ODI at 1, 6, and 12 months follow-up. Epidural application of steroid has a better effect on controlling the postoperative pain of PELD in the short term. The epidural application of steroid did not show a tendency to cause infection.
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spelling pubmed-63927482019-03-15 Epidural versus intravenous steroids application following percutaneous endoscopic lumbar discectomy Hu, Annan Gu, Xin Guan, Xiaofei Fan, Guoxin He, Shisheng Medicine (Baltimore) Research Article Retrospectively study. The purpose of this study was to compare the effects of intraoperative epidural steroids and single dose intravenous steroids following a percutaneous endoscopic lumbar discectomy (PELD). Inflammatory irritation of dorsal root ganglia or sensory nerve roots may cause postoperative pain. Epidural steroids have been applied after a lumbar discectomy for more than 20 years. Epidural steroid application after a PELD is easier to perform and safer because the operations are under observation of the scope. We retrospectively reviewed the medical records of patients with lumbar intervertebral disc herniation who had undergone transforaminal PELD at our department. There are 60 patients in epidural steroid group, intravenous steroid group, and control group, respectively. Visual analog scores (VAS) and the Oswestry Disability Index (ODI) were collected. Successful pain control is defined as 50% or more reduction in back and leg pain (VAS scores). VAS scores (back and leg) and ODI showed a significant decrease in all groups when comparing pre- and postoperatively. Epidural steroid group had a significant improvement in successful pain control compared with the control group at 2 weeks of follow-up. VAS scores (leg) in the epidural steroid group showed a significant decrease compared with the intravenous steroids group at 1, 3, and 7 days after the surgery, but this difference had no statistical significance at 1, 6, and 12 months of follow-up. All groups did not show a significant difference in ODI at 1, 6, and 12 months follow-up. Epidural application of steroid has a better effect on controlling the postoperative pain of PELD in the short term. The epidural application of steroid did not show a tendency to cause infection. Wolters Kluwer Health 2018-05-04 /pmc/articles/PMC6392748/ /pubmed/29718884 http://dx.doi.org/10.1097/MD.0000000000010654 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle Research Article
Hu, Annan
Gu, Xin
Guan, Xiaofei
Fan, Guoxin
He, Shisheng
Epidural versus intravenous steroids application following percutaneous endoscopic lumbar discectomy
title Epidural versus intravenous steroids application following percutaneous endoscopic lumbar discectomy
title_full Epidural versus intravenous steroids application following percutaneous endoscopic lumbar discectomy
title_fullStr Epidural versus intravenous steroids application following percutaneous endoscopic lumbar discectomy
title_full_unstemmed Epidural versus intravenous steroids application following percutaneous endoscopic lumbar discectomy
title_short Epidural versus intravenous steroids application following percutaneous endoscopic lumbar discectomy
title_sort epidural versus intravenous steroids application following percutaneous endoscopic lumbar discectomy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392748/
https://www.ncbi.nlm.nih.gov/pubmed/29718884
http://dx.doi.org/10.1097/MD.0000000000010654
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