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Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck

To analyze the superiority of wait-and-see policy and elective neck dissection in treating cN0 patients with facial cutaneous cell carcinoma (cSCC). Patients with clinically negative parotid and neck metastasis disease were prospectively enrolled. Three groups were divided based on whether the patie...

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Detalles Bibliográficos
Autores principales: Xiao, Yan, Yuan, Shuai, Liu, Fei, Liu, Bing, Zhu, Juanfang, He, Wei, Li, Wenlu, Kan, Quancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392757/
https://www.ncbi.nlm.nih.gov/pubmed/29851784
http://dx.doi.org/10.1097/MD.0000000000010782
Descripción
Sumario:To analyze the superiority of wait-and-see policy and elective neck dissection in treating cN0 patients with facial cutaneous cell carcinoma (cSCC). Patients with clinically negative parotid and neck metastasis disease were prospectively enrolled. Three groups were divided based on whether the patient received an operation of superficial parotidectomy or/and elective dissection, and regional control and disease-specific survival rates were compared. The occult parotid and neck metastasis rate was 20% and 16%, respectively. There was neck node metastasis without parotid metastasis in only 1 patient. All the node metastasis occurred in level II. Regional recurrence was noted in 16 (16%) patients, and 6 patients died of the disease. In the group undergoing superficial parotidectomy and elective neck dissection, 2 patients had neck node metastasis, and there was no disease-related death, further survival analysis indicated it had better regional control and disease-specific survival rates compared with the other 2 groups. Superficial parotidectomy and elective neck dissection are suggested for patients with T3–4 facial cutaneous squamous cell carcinoma.