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Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck
To analyze the superiority of wait-and-see policy and elective neck dissection in treating cN0 patients with facial cutaneous cell carcinoma (cSCC). Patients with clinically negative parotid and neck metastasis disease were prospectively enrolled. Three groups were divided based on whether the patie...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392757/ https://www.ncbi.nlm.nih.gov/pubmed/29851784 http://dx.doi.org/10.1097/MD.0000000000010782 |
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author | Xiao, Yan Yuan, Shuai Liu, Fei Liu, Bing Zhu, Juanfang He, Wei Li, Wenlu Kan, Quancheng |
author_facet | Xiao, Yan Yuan, Shuai Liu, Fei Liu, Bing Zhu, Juanfang He, Wei Li, Wenlu Kan, Quancheng |
author_sort | Xiao, Yan |
collection | PubMed |
description | To analyze the superiority of wait-and-see policy and elective neck dissection in treating cN0 patients with facial cutaneous cell carcinoma (cSCC). Patients with clinically negative parotid and neck metastasis disease were prospectively enrolled. Three groups were divided based on whether the patient received an operation of superficial parotidectomy or/and elective dissection, and regional control and disease-specific survival rates were compared. The occult parotid and neck metastasis rate was 20% and 16%, respectively. There was neck node metastasis without parotid metastasis in only 1 patient. All the node metastasis occurred in level II. Regional recurrence was noted in 16 (16%) patients, and 6 patients died of the disease. In the group undergoing superficial parotidectomy and elective neck dissection, 2 patients had neck node metastasis, and there was no disease-related death, further survival analysis indicated it had better regional control and disease-specific survival rates compared with the other 2 groups. Superficial parotidectomy and elective neck dissection are suggested for patients with T3–4 facial cutaneous squamous cell carcinoma. |
format | Online Article Text |
id | pubmed-6392757 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-63927572019-03-15 Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck Xiao, Yan Yuan, Shuai Liu, Fei Liu, Bing Zhu, Juanfang He, Wei Li, Wenlu Kan, Quancheng Medicine (Baltimore) Research Article To analyze the superiority of wait-and-see policy and elective neck dissection in treating cN0 patients with facial cutaneous cell carcinoma (cSCC). Patients with clinically negative parotid and neck metastasis disease were prospectively enrolled. Three groups were divided based on whether the patient received an operation of superficial parotidectomy or/and elective dissection, and regional control and disease-specific survival rates were compared. The occult parotid and neck metastasis rate was 20% and 16%, respectively. There was neck node metastasis without parotid metastasis in only 1 patient. All the node metastasis occurred in level II. Regional recurrence was noted in 16 (16%) patients, and 6 patients died of the disease. In the group undergoing superficial parotidectomy and elective neck dissection, 2 patients had neck node metastasis, and there was no disease-related death, further survival analysis indicated it had better regional control and disease-specific survival rates compared with the other 2 groups. Superficial parotidectomy and elective neck dissection are suggested for patients with T3–4 facial cutaneous squamous cell carcinoma. Wolters Kluwer Health 2018-06-01 /pmc/articles/PMC6392757/ /pubmed/29851784 http://dx.doi.org/10.1097/MD.0000000000010782 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 |
spellingShingle | Research Article Xiao, Yan Yuan, Shuai Liu, Fei Liu, Bing Zhu, Juanfang He, Wei Li, Wenlu Kan, Quancheng Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck |
title | Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck |
title_full | Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck |
title_fullStr | Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck |
title_full_unstemmed | Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck |
title_short | Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck |
title_sort | comparison between wait-and-see policy and elective neck dissection in clinically n0 cutaneous squamous cell carcinoma of head and neck |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392757/ https://www.ncbi.nlm.nih.gov/pubmed/29851784 http://dx.doi.org/10.1097/MD.0000000000010782 |
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