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Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck

To analyze the superiority of wait-and-see policy and elective neck dissection in treating cN0 patients with facial cutaneous cell carcinoma (cSCC). Patients with clinically negative parotid and neck metastasis disease were prospectively enrolled. Three groups were divided based on whether the patie...

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Autores principales: Xiao, Yan, Yuan, Shuai, Liu, Fei, Liu, Bing, Zhu, Juanfang, He, Wei, Li, Wenlu, Kan, Quancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392757/
https://www.ncbi.nlm.nih.gov/pubmed/29851784
http://dx.doi.org/10.1097/MD.0000000000010782
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author Xiao, Yan
Yuan, Shuai
Liu, Fei
Liu, Bing
Zhu, Juanfang
He, Wei
Li, Wenlu
Kan, Quancheng
author_facet Xiao, Yan
Yuan, Shuai
Liu, Fei
Liu, Bing
Zhu, Juanfang
He, Wei
Li, Wenlu
Kan, Quancheng
author_sort Xiao, Yan
collection PubMed
description To analyze the superiority of wait-and-see policy and elective neck dissection in treating cN0 patients with facial cutaneous cell carcinoma (cSCC). Patients with clinically negative parotid and neck metastasis disease were prospectively enrolled. Three groups were divided based on whether the patient received an operation of superficial parotidectomy or/and elective dissection, and regional control and disease-specific survival rates were compared. The occult parotid and neck metastasis rate was 20% and 16%, respectively. There was neck node metastasis without parotid metastasis in only 1 patient. All the node metastasis occurred in level II. Regional recurrence was noted in 16 (16%) patients, and 6 patients died of the disease. In the group undergoing superficial parotidectomy and elective neck dissection, 2 patients had neck node metastasis, and there was no disease-related death, further survival analysis indicated it had better regional control and disease-specific survival rates compared with the other 2 groups. Superficial parotidectomy and elective neck dissection are suggested for patients with T3–4 facial cutaneous squamous cell carcinoma.
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spelling pubmed-63927572019-03-15 Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck Xiao, Yan Yuan, Shuai Liu, Fei Liu, Bing Zhu, Juanfang He, Wei Li, Wenlu Kan, Quancheng Medicine (Baltimore) Research Article To analyze the superiority of wait-and-see policy and elective neck dissection in treating cN0 patients with facial cutaneous cell carcinoma (cSCC). Patients with clinically negative parotid and neck metastasis disease were prospectively enrolled. Three groups were divided based on whether the patient received an operation of superficial parotidectomy or/and elective dissection, and regional control and disease-specific survival rates were compared. The occult parotid and neck metastasis rate was 20% and 16%, respectively. There was neck node metastasis without parotid metastasis in only 1 patient. All the node metastasis occurred in level II. Regional recurrence was noted in 16 (16%) patients, and 6 patients died of the disease. In the group undergoing superficial parotidectomy and elective neck dissection, 2 patients had neck node metastasis, and there was no disease-related death, further survival analysis indicated it had better regional control and disease-specific survival rates compared with the other 2 groups. Superficial parotidectomy and elective neck dissection are suggested for patients with T3–4 facial cutaneous squamous cell carcinoma. Wolters Kluwer Health 2018-06-01 /pmc/articles/PMC6392757/ /pubmed/29851784 http://dx.doi.org/10.1097/MD.0000000000010782 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle Research Article
Xiao, Yan
Yuan, Shuai
Liu, Fei
Liu, Bing
Zhu, Juanfang
He, Wei
Li, Wenlu
Kan, Quancheng
Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck
title Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck
title_full Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck
title_fullStr Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck
title_full_unstemmed Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck
title_short Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck
title_sort comparison between wait-and-see policy and elective neck dissection in clinically n0 cutaneous squamous cell carcinoma of head and neck
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392757/
https://www.ncbi.nlm.nih.gov/pubmed/29851784
http://dx.doi.org/10.1097/MD.0000000000010782
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